Effects of ozone autohemotherapy on blood VEGF, TGF-β and PDGF levels after finger replantation
| Autor: | Zhongbin Lai, Shuiqi Cai, Weiting Chen, Ji Yao, Shaoyi He, Di Yu, Jingzhao Xia |
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| Rok vydání: | 2020 |
| Předmět: |
Vascular Endothelial Growth Factor A
0301 basic medicine Visual analogue scale Anastomosis Autohemotherapy Microcirculation Fingers 03 medical and health sciences chemistry.chemical_compound Ozone 0302 clinical medicine Transforming Growth Factor beta White blood cell medicine Humans Survival rate Platelet-Derived Growth Factor Advanced and Specialized Nursing business.industry Blood flow Vascular endothelial growth factor 030104 developmental biology Anesthesiology and Pain Medicine medicine.anatomical_structure chemistry Replantation 030220 oncology & carcinogenesis Anesthesia business |
| Zdroj: | Annals of Palliative Medicine. 9:3332-3339 |
| ISSN: | 2224-5839 2224-5820 |
| Popis: | BACKGROUND The study aimed to confirm the important role of ozone autologous blood therapy (autohemotherapy) in promoting successful finger replantation and its possible influence mechanism. METHODS A total of 150 patients with severed finger replantation admitted to our hospital from March 2018 to March 2019 were selected. Patients were divided into observation group and control group according to different treatment methods. The observation group received additional ozone autologous blood treatment in the control group. We compared the number of white blood cells, visual analogue scale (VAS) scores, and the expression levels of vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β), and platelet-derived growth factor (PDGF) in the two groups of patients before and after intervention. We also assessed the hospitalization time and survival time of the replanted finger in the two groups, as well as blood flow values (Vbcf). RESULTS Compared with the observation group on the 1st day after the operation and the control group on the 7th day after the operation, the average white blood cell count of the observation group on the 7th day after the operation was significantly increased (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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