Human metapneumovirus in Southern Brazil
| Autor: | Tatiana Schäffer Gregianini, Ivone Menegolla, Vagner Ricardo Lunge, Claudete Farina Seadi, Nilo Ikuta, Letícia Garay Martins, Jonas Michel Wolf |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Epidemiology viruses Severity of Illness Index 0302 clinical medicine Nasopharynx Prevalence Medicine Respiratory system Young adult Child Respiratory Distress Syndrome education.field_of_study Paramyxoviridae Infections biology Incidence (epidemiology) virus diseases Middle Aged Infectious Diseases Fluorescent Antibody Technique Direct Child Preschool Acute Disease Female Brazil Adult Microbiology (medical) medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine Adolescent lcsh:RC955-962 030231 tropical medicine 030106 microbiology Population Respiratory Syncytial Virus Infections Real-Time Polymerase Chain Reaction Virus Young Adult 03 medical and health sciences Human metapneumovirus Human respiratory syncytial virus Humans education Direct fluorescent antibody Respiratory viruses business.industry Infant Newborn Infant biology.organism_classification Virology respiratory tract diseases Respiratory Syncytial Virus Human Parasitology Metapneumovirus business |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical v.51 n.1 2018 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 1, Pp 30-38 Revista da Sociedade Brasileira de Medicina Tropical, Volume: 51, Issue: 1, Pages: 30-38, Published: FEB 2018 |
| Popis: | INTRODUCTION Infections caused by respiratory viruses are important problems worldwide, especially in children. Human metapneumovirus (hMPV) is a respiratory pathogen and causes severe infections with nonspecific symptoms. This study reports the hMPV occurrence and dissemination in southern Brazil and compares the frequency of occurrence of this virus and the human respiratory syncytial virus (hRSV) in the epidemiological weeks in a three-year period (2009-2011). METHODS: In total, 545 nasopharyngeal (NP) specimens from individuals with Severe Acute Respiratory Syndrome (SARS) who were negative for other seven respiratory viruses were analyzed for the presence of hMPV. Human metapneumovirus was detected by direct immunofluorescence and real-time reverse transcription polymerase chain reaction. RESULTS: hMPV was detected in 109 patients from the main geographic regions of the southernmost state of Brazil, presenting similar overall prevalence in males (46.8%) and females (53.2%). Among children who were less than six years old, hMPV was detected in 99 samples of all age groups, with a higher frequency in infants who were less than one year old (45.7%) compared to all other age groups until six years. hMPV and hRSV infection occurred in almost the same epidemiological weeks (EWs) of each year, with peaks of incidence between EW 31/37 and EW 26/38 for the years 2009 and 2011, respectively. hMPV was further detected in several cases of SARS and it was the only virus detected in three deaths. CONCLUSIONS These findings indicate that hMPV is in circulation in southern Brazil and highlight the importance of diagnosing hMPV for influenza-like illness in the population. |
| Databáze: | OpenAIRE |
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