Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology

Autor:	López-Contreras Ana Karen, Olvera-Montaño Cecilia, Rodríguez-Carrizalez Adolfo Daniel, Cardona-Muñoz Ernesto Germán, Navarro-Partida José, Robles-Rivera Ricardo Raúl, Roman-Pintos Luis Miguel, Castellanos-González José Alberto
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	0301 basic medicine Endocrinology Diabetes and Metabolism Inflammation Review Article Bioinformatics medicine.disease_cause lcsh:Diseases of the endocrine glands. Clinical endocrinology Antioxidants 03 medical and health sciences Ocular physiology 0302 clinical medicine Endocrinology Risk Factors Diabetes mellitus medicine Diabetes Mellitus Animals Humans Cellular degeneration Vision Ocular lcsh:RC648-665 Diabetic Retinopathy business.industry Diabetic retinopathy medicine.disease Pathophysiology Oxidative Stress 030104 developmental biology 030221 ophthalmology & optometry Disease Progression medicine.symptom Complication business Oxidative stress
Zdroj:	Journal of Diabetes Research Journal of Diabetes Research, Vol 2019 (2019)
ISSN:	2314-6753 2314-6745
Popis:	Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In this review, we propose oxidative stress as the focus point of this complication onset.
Databáze:	OpenAIRE
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