Left ventricular hypertrophy in hypertensive type 2 diabetic patients according to renal function
| Autor: | H Mérault, A. Blanchet Deverly, K. Hue, P. Kangambega, J.-P. Donnet, Lydia Foucan |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Population Statistics as Topic Renal function Type 2 diabetes Left ventricular hypertrophy Kidney Function Tests Muscle hypertrophy Endocrinology Renal Dialysis Risk Factors Internal medicine Internal Medicine medicine Humans cardiovascular diseases Obesity Renal Insufficiency education Dialysis Antihypertensive Agents Cause of death Aged education.field_of_study business.industry General Medicine Middle Aged medicine.disease Pulse pressure Cross-Sectional Studies Diabetes Mellitus Type 2 Cardiovascular Diseases Echocardiography Hypertension Cardiology Female Hypertrophy Left Ventricular business |
| Zdroj: | Diabetesmetabolism. 35(4) |
| ISSN: | 1878-1780 |
| Popis: | Cardiovascular disease is the main cause of death in diabetic patients undergoing haemodialysis. Dialysis and hypertension increase left ventricular hypertrophy (LVH), a strong predictor of cardiovascular events. This study evaluated left ventricular structure and function in three groups of hypertensive type 2 diabetic patients with different renal function, and assessed the factors associated with LVH, in an Afro-Caribbean population.Left ventricular structure and function were measured by ultrasonography. Group 1 consisted of 150 patients with normal renal function, group 2 included 183 patients with renal dysfunction and the third group comprised 75 dialysis patients.Left ventricular mass/height(2.7) increased from group 1 to groups 2 and 3 (49.00g/m(2.7), 57.12g/m(2.7) and 59.75g/m(2.7), respectively; P0.0001). The prevalences of LVH were 48.3% in group 1, 64.8% in group 2 and 70.3% in the dialysis patients (P=0.001). LVH was more concentric than eccentric in groups 2 and 3. The factors significantly associated with LVH were obesity in groups 1 and 2, and an increase of 10mmHg in pulse pressure in groups 2 and 3, according to multivariate logistic-regression analysis.Our study confirmed that, in a population of Afro-Caribbean hypertensive type 2 diabetic patients, renal failure was associated to an increased left ventricular mass/height(2.7). The data show that the variables associated with LVH differ according to renal profile. This finding will be of value in the treatment and follow-up of these patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect