Factors correlated with visual outcomes at two and four years after vitreous surgery for proliferative diabetic retinopathy

Autor: Teiko Yamamoto, Koichi Nishitsuka, Katsuhiro Nishi, Hidetoshi Yamashita
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Visual acuity
Eye Diseases
Vision
medicine.medical_treatment
Visual Acuity
Social Sciences
Vitrectomy
Severity of Illness Index
0302 clinical medicine
Medical Conditions
Endocrinology
Medicine and Health Sciences
Odds Ratio
Psychology
Multidisciplinary
Ophthalmic Procedures
Retinal detachment
Diabetic retinopathy
Middle Aged
Retinal Disorders
Medicine
Sensory Perception
Female
medicine.symptom
Anatomy
Research Article
medicine.medical_specialty
Endocrine Disorders
Science
030209 endocrinology & metabolism
Surgical and Invasive Medical Procedures
Vitreoretinal Surgery
03 medical and health sciences
Ocular System
Ophthalmology
Severity of illness
medicine
Diabetes Mellitus
Humans
Aged
Retrospective Studies
Rubeosis iridis
Diabetic Retinopathy
business.industry
Cognitive Psychology
Retinal Detachment
Biology and Life Sciences
Odds ratio
medicine.disease
Vitreous Hemorrhage
Logistic Models
Metabolic Disorders
Vitreous hemorrhage
030221 ophthalmology & optometry
Cognitive Science
Eyes
Perception
Ocular Hypertension
business
Head
Neuroscience
Zdroj: PLoS ONE, Vol 16, Iss 1, p e0244281 (2021)
PLoS ONE
ISSN: 1932-6203
Popis: Proliferative diabetic retinopathy (PDR) is the most severe case of diabetic retinopathy that can cause visual impairment. This study aimed to reveal the factors correlated with better postoperative visual acuity after a long follow-up in patients who underwent vitrectomy for PDR. We retrospectively analyzed the data set including systemic findings, ocular findings, and surgical factors from registered patients who could be completely followed up for 2 or 4 years after vitrectomy. We ultimately enrolled 128 eyes from 100 patients who underwent vitrectomy for PDR between January 2008 and September 2012 and were followed up for >2 years. Among them, 91 eyes from 70 patients could be followed up for 4 years. Factors related to the postoperative visual acuity of ≥20/40 and ≥20/30 after 2 and 4 years were investigated by logistic regression analysis. Better postoperative visual acuity correlated with the following factors: no rubeosis iridis ([≥20/40 at 2 years; odds ratio {OR}, 0.068; 95% confidence interval {CI}, 0.012–0.39; P = 0.003], [≥20/30 at 2 years; OR, 0.07; 95% CI, 0.01–0.40; P = 0.03], [≥20/30 at 4 years; OR, 0.078; 95% CI, 0.006–0.96; P = 0.04]), no fibrovascular membrane [(≥20/40 at 2 years; OR, 0.22; 95% CI, 0.061–0.81; P = 0.02), (≥20/40 at 4 years; OR, 0.26; 95% CI, 0.07–0.94; P = 0.04), (≥20/30 at 4 years; OR, 0.14; 95% CI, 0.04–0.52; P = 0.004)], existing vitreous hemorrhage (≥20/30 at 2 years; OR, 9.55; 95% CI, 1.03–95.27; P = 0.04), and no reoperation ([≥20/40 at 4 years; OR, 0.15; 95% CI, 0.03–0.78; P = 0.02], [≥20/30 at 4 years; OR, 0.06; 95% CI, 0.07–0.54; P = 0.01]). Treatment provision before disease severity and treatment without complications were associated with good postoperative visual acuity.
Databáze: OpenAIRE
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