Disappearance of an anticoagulation–resistant left atrial appendage thrombus after administration of low–dose pimobendan
| Autor: | Takuryu Sonoura, Takayuki Sekihara, Yu Morishita, Masashi Ishimi, Yuka Nakamura, Isamu Sunayama, Takahiro Yoshimura, Yoshinori Yasuoka, Masashi Yamato |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Inotrope
medicine.medical_specialty business.industry Low dose Warfarin Atrial fibrillation 030204 cardiovascular system & hematology medicine.disease Article Dabigatran 03 medical and health sciences 0302 clinical medicine Pimobendan Left atrial Internal medicine medicine Cardiology cardiovascular system 030212 general & internal medicine cardiovascular diseases Thrombus Cardiology and Cardiovascular Medicine business medicine.drug circulatory and respiratory physiology |
| Popis: | Anticoagulation therapy is essential for preventing thrombus formation in the left atrial appendage (LAA) and subsequent ischemic strokes in patients with atrial fibrillation (AF). The complete disappearance of any existing LAA thrombi is crucial before AF ablation. Currently, warfarin and direct oral anticoagulants are widely used for this purpose. However, treatment strategies for anticoagulation-resistant LAA thrombi are not well established. Here, we present a case of an 85-year-old male who was scheduled to undergo AF ablation. He developed an LAA thrombus that was resistant to 300 mg/day of dabigatran. Low-dose pimobendan was prescribed in addition to dabigatran; three months later, the thrombus was dissolved successfully. This case demonstrates the potential efficacy of a low-dose oral inotrope for treating an anticoagulation-resistant LAA thrombus. |
| Databáze: | OpenAIRE |
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