Assessing the subjective effects of stimulants in casual users. A methodology and preliminary results
| Autor: | Harrison G. Pope, Jonathan O. Cole, Martin Ionescu-Pioggia, Richard A. LaBrie |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Drug
Adult Male Dextroamphetamine Time Factors Casual media_common.quotation_subject medicine.medical_treatment Analgesic Emotions Anxiety Placebo Placebos chemistry.chemical_compound Nefopam Caffeine medicine Humans Pharmacology (medical) Fatigue media_common Pharmacology business.industry Depression Illicit Drugs Euphoria Stimulant Clinical trial chemistry Anesthesia Central Nervous System Stimulants Female business Clinical psychology medicine.drug |
| Zdroj: | Clinical pharmacology and therapeutics. 24(2) |
| ISSN: | 0009-9236 |
| Popis: | In order to assess the subjective effects of nefopam, a new non-opiate analgesic, a study was designed using highly educated, young, middle-to-upper class subjects in a naturalistic setting. Results suggest that the design is capable of differentiating variations in subjective drug effects. On a number of measures, 10 mg of d-amphetamine, a modest dosage, could be distinguished from placebo, showing changes in the direction expected for stimulant drugs. Nefopam (90 mg), on the other hand, showed few differences from placebo or caffeine (300 mg). Nefopam appeared mildly dysphoric, rather than stimulant, in subjective effects. |
| Databáze: | OpenAIRE |
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