Profiling Fragile X Syndrome in males: Strengths and weaknesses in cognitive abilities

Autor: G.J.A. Ramakers, B.J.C. Hamel, K.R. Ridderinkhof, Hilde M. Huizenga, Leopold M.G. Curfs, M.W. van der Molen, M.W. Van der Molen, Mariëtte Huizinga
Přispěvatelé: Netherlands Institute for Neuroscience (NIN), Ontwikkelingspsychologie (Psychologie, FMG), Brein en Cognitie (Psychologie, FMG), Educational Neuroscience, MUMC+: DA KG Polikliniek (9), Beleid Economie & Organisatie vd Zorg, Genetica & Celbiologie, RS: CAPHRI School for Public Health and Primary Care, RS: GROW - School for Oncology and Reproduction
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Adult
Male
Adolescent
Psychometrics
Spatial ability
Short-term memory
Cognitive profile
Neuropsychological Tests
Severity of Illness Index
Vocabulary
behavioral disciplines and activities
Developmental psychology
Executive control
Genomic disorders and inherited multi-system disorders [IGMD 3]
Executive Function
Young Adult
Borderline intellectual functioning
Intellectual Disability
Developmental and Educational Psychology
medicine
Humans
Effects of sleep deprivation on cognitive performance
Mental age
Intelligence Tests
Verbal Behavior
Subgroups
Cognition
Middle Aged
medicine.disease
Model-based cluster analysis
Fragile X syndrome
Developmental disorder
Clinical Psychology
Memory
Short-Term
Pattern Recognition
Visual
Fragile X Syndrome
Cognition Disorders
Psychology
Functional Neurogenomics [DCN 2]
Zdroj: Research in Developmental Disabilities, 31, 2, pp. 426-39
Research in Developmental Disabilities, 31, 426-439. Elsevier B.V.
Research in Developmental Disabilities, 31, 426-39
Research in Developmental Disabilities, 31(2), 426-439. Elsevier
Research in Developmental Disabilities, 31(2), 426-439. Elsevier Inc.
Research in Developmental Disabilities, 31(2), 426-439. Elsevier Science
Van der Molen, M W J, Huizinga, M, Huizenga, H M, Ridderinkhof, K R, Hamel, B J C & Ramakers, G J A 2010, ' Profiling Fragile X Syndrome in Males: Strengths and weaknesses in cognitive abilities ', Research in Developmental Disabilities, vol. 31, no. 2, pp. 426-439 . https://doi.org/10.1016/j.ridd.2009.10.013
ISSN: 0891-4222
DOI: 10.1016/j.ridd.2009.10.013
Popis: The present study examined the cognitive profile in Fragile X Syndrome (FXS) males, and investigated whether cognitive profiles are similar for FXS males at different levels of intellectual functioning. Cognitive abilities in non-verbal, verbal, memory and executive functioning domains were contrasted to both a non-verbal and verbal mental age reference. Model-based cluster analyses revealed three distinct subgroups which differed in level of functioning, but showed similar cognitive profiles. Results showed that cognitive performance is particularly weak on measures of reasoning- and performal abilities confined to abstract item content, but relatively strong on measures of visuo-perceptual recognition and vocabulary. Further, a significant weakness was found for verbal short-term memory. Finally, these results indicated that the choice of an appropriate reference is critically important in examining cognitive profiles. The pattern of findings that emerged from the current cognitive profiling of FXS males was interpreted to suggest a fundamental deficit in executive control.
Databáze: OpenAIRE
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