Conservative versus conventional oxygen therapy for cardiac surgical patients: A before-and-after study

Autor: Hidetoshi Kagaya, Helen Young, Sean D. Galvin, George Matalanis, Neil J Glassford, Rinaldo Bellomo, Satoshi Suzuki, Matthew J Chan, Glenn M Eastwood, Leah Peck, Johan Mårtensson
Rok vydání: 2019
Předmět:
Zdroj: Anaesthesia and Intensive Care. 47:175-182
ISSN: 1448-0271
0310-057X
DOI: 10.1177/0310057x19838753
Popis: Avoiding hypoxaemia is considered crucial in cardiac surgery patients admitted to the intensive care unit (ICU). However, avoiding hyperoxaemia may also be important. A conservative approach to oxygen therapy may reduce exposure to hyperoxaemia without increasing the risk of hypoxaemia. Using a before-and-after design, we evaluated the introduction of conservative oxygen therapy (target SpO2 88%–92% using the lowest FiO2) for cardiac surgical patients admitted to the ICU. We studied 9041 arterial blood gas (ABG) datasets: 4298 ABGs from 245 ‘conventional’ and 4743 ABGs from 298 ‘conservative’ oxygen therapy patients. During mechanical ventilation (MV) and while in the ICU, compared to the conventional group, conservative group patients had significantly lower FiO2 exposure and PaO2 values ( P 2 during MV, more conservative group patients were classified as normoxaemic (226 versus 62 patients, P
Databáze: OpenAIRE