Characteristics, management and survival of ICU patients with coronavirus disease‐19 in Norway, March‐June 2020. A prospective observational study

Autor: Kristin Hofsø, Jon Henrik Laake, Eirik Alnes Buanes, Reidar Kvåle, Vibecke Sørensen, Kristian Strand, Milada Cvancarova Småstuen, Brita Fosser Olsen, Tone Rustøen
Rok vydání: 2021
Předmět:
Male
Time Factors
medicine.medical_treatment
Prone ventilation
0302 clinical medicine
Patient survivals
Prospective Studies
030212 general & internal medicine
national cohort
Aged
80 and over
Patient characteristics
Norway
General Medicine
Middle Aged
COVID-19 patients
Intensive Care Units
Cohort
Health Resources
Original Article
Female
Adult
medicine.medical_specialty
SARS‐CoV2
mechanical ventilation
03 medical and health sciences
Medisinske Fag: 700 [VDP]
Intensive care
Severity of illness
medicine
Humans
Norwegian intensive care units
Renal replacement therapy
covid‐19
Aged
Mechanical ventilation
SARS-CoV-2
business.industry
Proportional hazards model
COVID-19
030208 emergency & critical care medicine
Original Articles
Length of Stay
Intensivsykepleie
Anesthesiology and Pain Medicine
Respiratory failure
ICU
Emergency medicine
Patient management
ARDS
business
Zdroj: Acta Anaesthesiologica Scandinavica
ISSN: 1399-6576
0001-5172
DOI: 10.1111/aas.13785
Popis: Background: Norwegian hospitals have operated within capacity during the COVID-19 pandemic. We present patient and management characteristics, and outcomes for the entire cohort of adult (>18 years) COVID-19 patients admitted to Norwegian intensive care units (ICU) from 10 March to 19 June 2020. Methods: Data were collected from The Norwegian intensive care and pandemic registry (NIPaR). Demographics, co-morbidities, management characteristics and outcomes are described. ICU length of stay (LOS) was analysed with linear regression, and associations between risk factors and mortality were quantified using Cox regression. Results: In total, 217 patients were included. The male to female ratio was 3:1 and the median age was 63 years. A majority (70%) had one or more co-morbidities, most frequently cardiovascular disease (39%), chronic lung disease (22%), diabetes mellitus (20%), and obesity (17%). Most patients were admitted for acute hypoxaemic respiratory failure (AHRF) (91%) and invasive mechanical ventilation (MV) was used in 86%, prone ventilation in 38% and 25% of patients received a tracheostomy. Vasoactive drugs were used in 79% and renal replacement therapy in 15%. Median ICU LOS and time of MV was 14.0 and 12.0 days. At end of follow-up 45 patients (21%) were dead. Age, co-morbidities and severity of illness at admission were predictive of death. Severity of AHRF and male gender were associated with LOS. Conclusions: In this national cohort of COVID-19 patients, mortality was low and attributable to known risk factors. Importantly, prolonged length-of-stay must be taken into account when planning for resource allocation for any next surge. This study was funded by The Norwegian Research Council and Oslo University Hospital.
Databáze: OpenAIRE
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