First Occurrence of Megastigmane Glucosides in a Plant of Retama Genus

Autor:	Sara Ouissem Bensaid, Marianna Carbone, Letizia Palomba, Sabrina Bicha, Ali Bentamene, Arianna Carannante, Margherita Gavagnin, Maria Letizia Ciavatta
Rok vydání:	2022
Předmět:	Mice Glucosides Molecular Structure Algeria Molecular Medicine Animals Bioengineering Fabaceae General Chemistry General Medicine Norisoprenoids Molecular Biology Biochemistry
Zdroj:	Chemistrybiodiversity. 19(11)
ISSN:	1612-1880
Popis:	Chemical investigation of Retama sphaerocarpa collected in Algeria resulted in the isolation of two megastigmane glucosides, compounds 1 and 2, along with a series of isoflavones and phenol derivatives. Compound 1, named retamoside, was new and its structure was determined by extensive application of spectroscopic methods, including HRMS, 1D and 2D NMR and CD. The anti-inflammatory properties of co-occurring main megastigmane, saurobaccioside B (2) and structurally related vomifoliol (3) on LPS-stimulated murine macrophages RAW 274.7 have been evaluated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfe9eef5023e8691ba0fcbe33582059 https://pubmed.ncbi.nlm.nih.gov/36253121 Zobrazit plný text záznamu Plný text