The epidemiology and management of ameloblastomas: A European multicenter study
Autor: | Lars Rasmusson, Francesco Cavarra, Jaana Hagström, Angela Ridwan-Pramana, Tania Rodríguez-Santamarta, Johanna Snäll, Marta Rui Ranz, Vincenzo Rocchetti, Tadej Dovšak, Lavinia Masu, Paolo Boffano, Nikolai Pavlov, Drago Jelovac, C. Meyer, Aleksei Andrianov, Tiia Tamme, Matteo Brucoli, Iva Doykova, Muhammad Ruslin, Vitomir S. Konstantinovic, Gerardo Tricarico, Andrii Hresko, Petia Pechalova, Juan Carlos de Vicente, Thomas Starch Jensen, Tymour Forouzanfar, A. Barrabé, Yurii Chepurnyi, Andrii Kopchak, Aurélien Louvrier, Anže Birk |
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Přispěvatelé: | Oral and Maxillofacial Surgery / Oral Pathology, AMS - Tissue Function & Regeneration, CCA - Cancer Treatment and quality of life |
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Epidemiology medicine.medical_treatment Radiography Enucleation Mandible Curettage Ameloblastoma 03 medical and health sciences 0302 clinical medicine Recurrence Maxilla medicine Humans Ostectomy business.industry 030206 dentistry Middle Aged medicine.disease 3. Good health Surgery Treatment Mandibular Neoplasms Otorhinolaryngology 030220 oncology & carcinogenesis Female Neoplasm Recurrence Local Oral Surgery Segmental resection business |
Zdroj: | Boffano, P, Cavarra, F, Tricarico, G, Masu, L, Brucoli, M, Ruslin, M, Forouzanfar, T, Ridwan-Pramana, A, Rodríguez-Santamarta, T, Rui Ranz, M, de Vicente, J C, Starch-Jensen, T, Pechalova, P, Pavlov, N, Doykova, I, Konstantinovic, V S, Jelovac, D, Barrabé, A, Louvrier, A, Meyer, C, Tamme, T, Andrianov, A, Dovšak, T, Birk, A, Hresko, A, Chepurnyi, Y, Kopchak, A, Snäll, J, Hagström, J, Rasmusson, L & Rocchetti, V 2021, ' The epidemiology and management of ameloblastomas : A European multicenter study ', Journal of Cranio-Maxillofacial Surgery, vol. 49, no. 12, pp. 1107-1112 . https://doi.org/10.1016/j.jcms.2021.09.007 Journal of Cranio-Maxillofacial Surgery, 49(12), 1107-1112. Churchill Livingstone |
ISSN: | 1010-5182 |
Popis: | The present study aimed at assessing the epidemiology including demographic variables, diagnostic features, and management of ameloblastomas at several European departments of maxillofacial and oral surgery. The following data were recorded for each patient: gender, age, voluptuary habits, comorbidities, site, size, radiographic features, type, histopathological features, kind of treatment, length of hospital stay, complications, recurrence, management and complications of the recurrence. A total of 244 patients, 134 males and 110 females with ameloblastomas were included in the study. Mean age was 47.4 years. In all, 81% of lesions were found in the mandible, whereas 19% were found in the maxilla. Mean size of included ameloblastomas was 38.9 mm. The most frequently performed treatment option was enucleation plus curettage/peripheral ostectomy in 94 ameloblastomas, followed by segmental resection (60 patients), simple enucleation (46 patients), and marginal resection (40 patients). A recurrence (with a mean follow up of 5 years) was observed in 47 cases out of 244 ameloblastomas (19.3%). Segmental resection was associated with a low risk of recurrence (p = 0003), whereas enucleation plus curettage/peripheral ostectomy was associated with a high risk of recurrence (p = 0002). A multilocular radiographic appearance was associated with a high risk of recurrence (p < .05), as well as the benign solid/multicystic histologic type (p < .05). Within the limitations of the study it seems that the management of ameloblastomas will probably remain controversial even in the future. Balancing low surgical morbidity with a low recurrence rate is a difficult aim to reach. |
Databáze: | OpenAIRE |
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