An experimentally induced phlegmonous abscess by a strain of Bacteroides gingivalis in guinea pigs and mice
Autor: | J. de Graaff, J. M. Bras, T. J. M. van Steenbergen, P. Kastelein |
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Rok vydání: | 1981 |
Předmět: |
Male
Guinea Pigs Virulence Anaerobic bacterium Microbiology Mice Necrosis Animal model medicine Animals Bacteroides Abscess Molecular Biology Inflammation biology Strain (chemistry) General Medicine Bacteroides Infections biology.organism_classification medicine.disease Rats Experimental animal Anaerobic bacteria |
Zdroj: | Antonie van Leeuwenhoek. 47:1-9 |
ISSN: | 1572-9699 0003-6072 |
Popis: | The virulence of B. gingivalis strain W83 was studied in an experimental animal model. Cells grown overnight, washed and resuspended in broth, were injected intradermally or subcutaneously in the back of guinea pigs, rats and mice. This strain proved to be very virulent, causing a severe phlegmonous abscess in guinea pigs. Also in mice, which are thought to be resistant to infections with black-pigmented Bacteroides strains, the same type of infection could be induced. Rats proved to be rather insensitive. The model presented can be used as a simple virulence test for these anaerobic bacteria. |
Databáze: | OpenAIRE |
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