Mixed ligand based copper(II) complex and its antimicrobial activity

Autor: R. Suhasini, Poonam R. Inamdar, A. Sheela
Jazyk: angličtina
Rok vydání: 2015
Předmět:
DOI: 10.5281/zenodo.5702680
Popis: Department of Chemistry, Auxilium College, Vellore-632 006, Tamilnadu, India Materials Chemistry Division, School of Advanced Sciences, VIT University, Vellore-632 014, Tamilnadu, India E-mail : asheela@vit.ac.in Transition metal complexes of mixed ligand systems have played a pivotal role in the development of inorganic chemistry. Metal chelates have been preferred for therapeutic applications over inorganic salts due to their tunable coordination geometries and their efficiency to bring about desirable effect at minimum dosage levels1 . Mixed ligand complexes of curcumin with bipyridine, phenanthroline and other ancillary ligands have been proved as efficient anticancer agents2 . In the current study, the synthesis of CuII complex of mixed ligands of diethylmalonate and salicylaldehyde, possessing similar binding modes as curcumin and salicylaldehyde is described. The synthesized complex [Cu(sal)(dem)].2H2O is characterized by UV-Visible, FT-IR and mass spectral techniques to ascertain the structure of complex. These types of complexes are expected to possess potential antimicrobial and anticancer applications.  
Databáze: OpenAIRE