Activity, Template Preference, and Compatibility of Components of RNA Replicase of Eastern Equine Encephalitis Virus

Autor:	Laura Sandra Lello, Agneta Miilimäe, Liubov Cherkashchenko, Ailar Omler, Rachel Skilton, Rachel Ireland, David Ulaeto, Andres Merits
Rok vydání:	2023
Předmět:	Virology Insect Science Immunology Microbiology
Zdroj:	Journal of Virology. 97
ISSN:	1098-5514 0022-538X
DOI:	10.1128/jvi.01368-22
Popis:	Eastern equine encephalitis virus (EEEV) usually cycles between Culiseta melanura mosquitoes and birds; however, it can also infect humans. EEEV has a positive-sense RNA genome that, in infected cells, serves as an mRNA for the P1234 polyprotein. P1234 undergoes a series of precise cleavage events producing four nonstructural proteins (nsP1-4) representing subunits of the RNA replicase. Here, we report the construction and properties of a
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf331ed92f9656fa8a8290c86707ea1 https://doi.org/10.1128/jvi.01368-22 Zobrazit plný text záznamu