Role of Cardiac Biomarkers in COVID-19: What Recent Investigations Tell Us?

Autor: Shahzad Khan, Syed Imran Ahmed, Sahibzada Tasleem Rasool
Rok vydání: 2021
Předmět:
CK-MB
creatine kinase-MB

AST
aspartate aminotransferase

030204 cardiovascular system & hematology
CTn
cardiac troponin

0302 clinical medicine
BNP
brain-type natriuretic peptide

CTnI
cardiac troponin I

Cardiovascular events
SARS-CoV-2

030212 general & internal medicine
DCM
diabetic cardiomyopathy

LDH
lactate dehydrogenase

General Medicine
CAP
community-acquired pneumonia

Prognosis
IHD
ischemic heart diseases

CVD
cardiovascular diseases

Organ damage
Cardiovascular Diseases
CRP
C-reactive protein

medicine.symptom
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
Cardiac biomarkers
ACE
angiotensin-converting enzyme

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Inflammation
MR-pro ANP
mid regional pro-atrial natriuretic peptide

SARS-CoV-2
severe acute respiratory syndrome coronavirus 2

Article
RAAS
Renin-Angiotensin-Aldosterone System

CHF
congestive heart failure

03 medical and health sciences
ALT
alanine aminotransferase

medicine
Humans
SARS
severe acute respiratory syndrome

Intensive care medicine
sST2
soluble source of tumorigenicity 2

NT-proBNP
N-terminal pro b-type natriuretic peptide

business.industry
SARS-CoV-2
CTnT
cardiac troponin T

COVID-19
2019 novel coronavirus disease

COVID-19
CK
Creatine kinase

AMI
acute myocardial infarction

COPD
chronic obstructive pulmonary disease

Cardiovascular Injury
ACS
acute coronary syndrome

ACovCS
acute COVID–19 cardiovascular syndrome

business
Biomarkers
Zdroj: Current Problems in Cardiology
ISSN: 1535-6280
Popis: Purpose of review: Although the respiratory system is the main target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is evident from recent data that other systems, especially cardiovascular and hematological, are also significantly affected. In fact, in severe form, COVID-19 causes a systemic illness with widespread inflammation and cytokine flood, resulting in severe cardiovascular injury. Therefore, we reviewed cardiac injury biomarkers' role in various cardiovascular complications of COVID 19 in recent studies. Recent findings: Cardiac injury biomarkers were elevated in most of the complicated cases of COVID-19, and their elevation is directly proportional to the worst outcome. Evaluation of cardiac biomarkers with markers of other organ damage gives a more reliable tool for case fatalities and future outcome. Summary: Significant association of cardiac biomarkers in COVID-19 cases helps disease management and prognosis, especially in severely ill patients.
Databáze: OpenAIRE