PROCORAD's international intercomparisons highlight the evolution of techniques used to determine uranium in urine

Autor: F. Briot, A. Montegue, J.-C. Harduin, P. Berard
Přispěvatelé: CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Centre CEA de Valduc (CEA-Valduc)
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Alpha spectrometry
Computer science
International Cooperation
urinalysis
[SDV]Life Sciences [q-bio]
radiation detection
030218 nuclear medicine & medical imaging
In vitro analysis
0302 clinical medicine
experience
radiochemistry
mass spectrometry
analytic method
Radiation
Radiological and Ultrasound Technology
accuracy
quantitative analysis
article
General Medicine
Repeatability
Uranium
Interinstitutional Relations
bioassay
030220 oncology & carcinogenesis
laboratory test
Systems engineering
France
Radioactive Pollutants
Societies
Scientific

in vitro study
competence
chemistry.chemical_element
Radiation Dosage
Sensitivity and Specificity
uranium
03 medical and health sciences
Occupational Exposure
personnel radiation monitoring
Humans
feces analysis
Radiology
Nuclear Medicine and imaging

controlled study
human
quality control
Radiometry
intermethod comparison
reproducibility
Analytical technique
Public Health
Environmental and Occupational Health

spectrofluorometry
Reproducibility of Results
chemistry
clinical protocol
radiation protection
Power Plants
Zdroj: RADIATION PROTECTION DOSIMETRY
RADIATION PROTECTION DOSIMETRY, 2003, 105 (1-4), pp.447-450. ⟨10.1093/oxfordjournals.rpd.a006279⟩
Popis: Inter-laboratory tests are a means of assessing the analytical coherence of medical laboratories. In radiotoxicology, this kind of exercise makes it possible to keep up with laboratory know-how and with the evolution and relative performances of analytical techniques. The intercomparison exercises organised by PROCORAD (Association for the Promotion of Quality Controls in Radiotoxicological Bioassays) provide an opportunity to compare and contrast radiochemistry and metrology for the in vitro analysis of urine and faeces. For uranium compounds, the development of new techniques such as inductively coupled plasma-mass spectrometry (ICP-MS), alpha spectrometry, and laser spectrofluorimetry makes it possible to compare the effectiveness of these protocols with respect to radiation protection monitoring, both in routine and special situations. Detection limits, flexibility, repeatability, reproducibility and isotopic quantification are the criteria considered in this study. The authors present the evolution of performances for the analysis of uranium in urine over the years. However, the goal of the laboratories taking part in these annual exercises is not only to check the accuracy of their results but also to have analytical discussions and the opportunity to exchange experiences that will enrich the group's general competence.
Databáze: OpenAIRE