Malaria parasite density estimation using actual and assumed white blood cell counts in Plasmodium falciparum-infected patients in Dak Lak province, Vietnam
| Autor: | Quang Hong Huynh, Nhien Thuy Thanh Nguyen, Hien Thanh Pham, Khanh Van Chau, Hong Duc Nguyen, Hien Tinh Tran |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
biology
business.industry Plasmodium falciparum Wbc count biology.organism_classification medicine.disease Efficacy medicine.anatomical_structure White blood cell parasitic diseases Immunology medicine Parasite hosting Malaria Parasite density Assumed white blood cell Actual white blood cell business |
| Zdroj: | World Journal of Advanced Research and Reviews. 7:241-245 |
| ISSN: | 2581-9615 |
| DOI: | 10.30574/wjarr.2020.7.3.0326 |
| Popis: | Estimating malaria parasite density is necessary for disease management, clinical trials and drug efficacy studies. This study was conducted to compare the malaria parasite density among patients using actual white blood cell (WBC) and the assumed WBC counts (8.0 ×109/l). A cross-sectional study was conducted in Dak Lak, Vietnam. WBC and asexual malaria parasite counts were performed on blood films. Eighty patients were enrolled. The mean (±SD) of WBCs was 5.84±1.63 ×109/l. The median (IQR) of parasite density using the assumed WBCs (8000 cells/µl) (11057.50 [2388.50-34210.75] rings/µl) was significantly higher than that estimation based on the actual WBC count (6898.61 [1892.12-24623.10] rings/µl) (pP. falciparum– infected patients in Dak Lak, Vietnam. |
| Databáze: | OpenAIRE |
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