Antineutrophil Cytoplasmic Antibody-associated Vasculitis after COVID-19 Vaccination with Pfizer-BioNTech

Autor: Minami Suzuki, Yuta Sekiguchi, Masato Sasaki, Shunsuke Inaba, Sakino Oyama, Yuichi Inoue, Masahiro Warabi, Kenichi Ohashi, Seiji Inoshita
Rok vydání: 2022
Předmět:
Zdroj: Internal medicine (Tokyo, Japan). 61(19)
ISSN: 1349-7235
Popis: The extent of rare side effects of mRNA vaccines for coronavirus disease 2019 (COVID-19) remains unclear. Several cases of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) following COVID-19 vaccination have been reported. We herein report a 72-year-old man who presented with a fever after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine. He was diagnosed with acute kidney injury due to myeloperoxidase-ANCA-associated vasculitis and was treated with intermittent hemodialysis, high-dose prednisolone, and intravenous rituximab. His general symptoms and renal impairment subsequently improved. When systemic symptoms are prolonged or renal abnormalities appear after COVID-19 vaccination, the possibility of AAV should be considered.
Databáze: OpenAIRE