Regioselective Nitration of N-Alkyl Anilines using tert-Butyl Nitrite under Mild Condition

Autor:	Priyanka Chaudhary, Shahulhameed Sabiah, Surabhi Gupta, Jeyakumar Kandasamy, Nalluchamy Muniyappan
Rok vydání:	2018
Předmět:	chemistry.chemical_classification Tert butyl 010405 organic chemistry Organic Chemistry Regioselectivity 010402 general chemistry Ring (chemistry) 01 natural sciences Medicinal chemistry 0104 chemical sciences chemistry.chemical_compound chemistry Nitration Nitrite Alkyl
Zdroj:	The Journal of Organic Chemistry. 84:104-119
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.8b02377
Popis:	Regioselective ring nitration of N-alkyl anilines is reported using tert-butyl nitrite. The reactions proceed efficiently with a wide range of substrates providing synthetically useful N-nitroso N-alkyl nitroanilines in excellent yields which can be easily converted into N-alkyl phenylenediamines and N-alkyl nitroanilines using Zn-AcOH and HCl/MeOH, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bda5f050124e926300444fc968bb1eb https://doi.org/10.1021/acs.joc.8b02377 Zobrazit plný text záznamu