Translocation t(15;17) in acute myelogenous leukemia with atypical megakaryoblastic features: Diagnostic, clinical, and therapeutic implications
Autor: | Thomas S. McConnell, Everardo Cobos, Vijay S. Tonk, Dale M. Dunn, David Morgan, Yi-Kong Keung |
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Rok vydání: | 1996 |
Předmět: |
Cancer Research
Adolescent Cellular differentiation Chromosomal translocation T-15 Biology medicine.disease Leukemia Myeloid Acute Myelogenous Leukemia Leukemia Megakaryoblastic Acute Pregnancy Karyotyping hemic and lymphatic diseases Immunology Genetics medicine Humans Female Megakaryocytes Pregnancy Complications Neoplastic Molecular Biology |
Zdroj: | Cancer Genetics and Cytogenetics. 92:50-53 |
ISSN: | 0165-4608 |
DOI: | 10.1016/s0165-4608(96)00158-6 |
Popis: | We describe the first reported case of acute myelogenous leukemia with characteristics of megakaryoblastic differentiation and the t(15;17) chromosomal translocation, which has been associated with promyelocytic leukemia. The diagnostic, clinical, and therapeutic implications are discussed. |
Databáze: | OpenAIRE |
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