Facile synthesis of chlorin bioconjugates by a series of click reactions

Autor:	Huong Chu, Naser Dodic, N. V. S. Dinesh K. Bhupathiraju, Julia Rozenberg, Nancy L. Greenbaum, Veronica Bueno, Charles Michael Drain, William Perea, Naxhije Berisha, Junior Gonzales
Rok vydání:	2017
Předmět:	Porphyrins Molecular Structure 010405 organic chemistry Oligonucleotide Oligonucleotides Metals and Alloys Proteins Nanotechnology General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Article Catalysis 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound chemistry Chlorin polycyclic compounds Materials Chemistry Ceramics and Composites Click Chemistry
Zdroj:	Chemical Communications. 53:3773-3776
ISSN:	1364-548X 1359-7345
DOI:	10.1039/c7cc01265a
Popis:	A multifunctional chlorin platform appended with four short polyethylene glycols and a carboxylate-linker allows rapid conjugation to biotargeting motifs such as proteins and oligonucleotides. The stability and photophysical properties of the chlorin enable development of diagnostics, imaging, molecular tracking, and theranostics.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc7d87bdad8ce20580d41e0dc4caece https://doi.org/10.1039/c7cc01265a Zobrazit plný text záznamu