Treatment of second to third-degree burns in a 2-day-old infant: A case report
| Autor: | Thomas Ziegler, Dieter Pögl, Johannes Schauer, Tomas Kempny, Thomas Cakl |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Heel medicine.medical_treatment OECD Organisation for Economic Co-operation and Development Poison control MSC mesenchymal stem cell Article 03 medical and health sciences 0302 clinical medicine HSC hematopoietic stem cell EPC endothelial progenitor cell Deformity Medicine Neonatal burn Iatrogenic burn EGF epidermal growth factor Debridement TBSA total body surface area Third-Degree Burn business.industry Infant VEGF vascular endothelial growth factor FGF fibroblast growth factor Surgery UCB umbilical cord blood HDF human dermal fibroblast medicine.anatomical_structure 030220 oncology & carcinogenesis Accidental Tissue regeneration Mesenchymal stem cells 030211 gastroenterology & hepatology medicine.symptom Non-surgical treatment business Wound healing Total body surface area VSEL very small embryonic-like stem cell |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| DOI: | 10.1016/j.ijscr.2019.07.035 |
| Popis: | Highlights • Therapy for high grade burns: immediate debridement, coverage with suitable dressings. • Post-burn scar contracture-surgery: at least one year after the burn injury. • Mobilization of Mesenchymal Stem Cells in infants is a autologous stem cell therapy. Introduction Burn injuries in newborns are particularly complex cases. Since these patients are rare, there is little experience and no existing standardized treatment. Presentation of case This report examines a case of accidental second to third-degree burning of the heel and toes on the left foot in a new-born girl. The burns covered an estimated 1% of the total body surface area (TBSA). After an initial debridement and 32 days of non-surgical wound therapy with Adaptic® fat gauze dressings, we were able to achieve an aesthetically and functionally satisfactory result including the complete preservation of all toes. In order to eliminate a scar contracture, we carried out a Z-plasty one year later. Discussion Modern wound treatment following the principle of less frequent dressing changes allows the burn wound to have better re-epithelialization. New findings in stem cell research indicate that the high proportion of mesenchymal stem cells (MSC) in postnatal blood is also involved in the regeneration and healing of burns. To our knowledge, this is the first case report dealing with initial non-surgical combustion therapy in a newborn. Conclusion There is evidence that newborns have a much higher potential for wound healing than adults. Proper position in long-term immobilization of toes is important to prevent scar contracture and deformity. |
| Databáze: | OpenAIRE |
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