Towards an improved access to psychiatric rehabilitation: availability and effectiveness at 1-year follow-up of psychoeducation, cognitive remediation therapy, cognitive behaviour therapy and social skills training in the FondaMental Advanced Centers of Expertise-Schizophrenia (FACE-SZ) national cohort

Autor: Bruno Aouizerate, Julien Dubreucq, David Misdrahi, Thierry d'Amato, E. Giraud-Baro, Delphine Capdevielle, Romain Rey, E. Bulzacka, Ophélia Godin, M. Andrianarisoa, Guillaume Fond, L. Boyer, Lore Brunel, Mathieu Urbach, Agnès Hamon, Bernard Ycart, Raphaëlle Richieri, Fabrice Berna, Caroline Dubertret, Christine Passerieux, F. Gabayet, Jasmina Mallet, A. Schandrin, Pierre-Michel Llorca, Claire-Cécile Perier, Pierre Vidailhet, F. Schürhoff, Isabelle Chereau, Catherine Faget
Přispěvatelé: Fondation FondaMental [Créteil], Centre Référent de Réhabilitation Psychosociale [CH Alpes Isère], Centre Hospitalier Alpes Isère, Statistique pour le Vivant et l’Homme (SVH), Laboratoire Jean Kuntzmann (LJK ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Neuro-Psycho Pharmacologie des Systèmes Dopimanégiques sous-corticaux (NPsy-Sydo), CHU Clermont-Ferrand-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Sommeil, Addiction et Neuropsychiatrie [Bordeaux] (SANPSY), Université de Bordeaux (UB)-CHU de Bordeaux Pellegrin [Bordeaux]-Centre National de la Recherche Scientifique (CNRS), Institut Européen des membranes (IEM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18) (Inserm U955), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Université Paris Diderot - Paris 7 (UPD7), Assistance Publique - Hôpitaux de Marseille (APHM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Departement de Psychiatrie, Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Université de Strasbourg (UNISTRA), Réseau Handicap Psychique RéHPSY, ANR-11-IDEX-0004,SUPER,Sorbonne Universités à Paris pour l'Enseignement et la Recherche(2011), ANR-10-COHO-0010,Psy-COH,FondaMental-Cohortes(2010), Sommeil, Attention et Neuropsychiatrie [Bordeaux] (SANPSY), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM), Assistance Publique-Hôpitaux de Marseille (AP-HM)
Rok vydání: 2018
Předmět:
Adult
Male
medicine.medical_specialty
medicine.medical_treatment
education.educational_degree
Psychological intervention
Psychiatric rehabilitation
Effectiveness
Health Services Accessibility
law.invention
Social Skills
03 medical and health sciences
Young Adult
0302 clinical medicine
Quality of life
Randomized controlled trial
Patient Education as Topic
law
Outpatients
Psychoeducation
Medicine
Humans
Pharmacology (medical)
Functioning
education
Biological Psychiatry
Cognitive Behavioral Therapy
business.industry
Rehabilitation
General Medicine
Middle Aged
Cognitive Remediation
3. Good health
030227 psychiatry
Psychiatry and Mental health
Cognitive remediation therapy
[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
Cohort
Physical therapy
Quality of Life
Schizophrenia
Female
Schizophrenic Psychology
business
Psychosocial interventions
Psychosocial
030217 neurology & neurosurgery
Follow-Up Studies
Zdroj: European Archives of Psychiatry and Clinical Neuroscience
European Archives of Psychiatry and Clinical Neuroscience, 2019, 269 (5), pp.599-610. ⟨10.1007/s00406-019-01001-4⟩
European Archives of Psychiatry and Clinical Neuroscience, Springer Verlag, 2019, 269 (5), pp.599-610. ⟨10.1007/s00406-019-01001-4⟩
ISSN: 1433-8491
0940-1334
DOI: 10.1007/s00406-019-01001-4⟩
Popis: International audience; Psychosocial Interventions (PIs) have shown positive effects on clinical and functional outcomes of schizophrenia (SZ) in randomized controlled trials. However their effectiveness and accessibility remain unclear to date in “real world” schizophrenia. The objectives of the present study were (i) to assess the proportion of SZ outpatients who benefited from PIs between 2010 and 2015 in France after an Expert Center Intervention in a national multicentric non-selected community-dwelling sample; (ii) to assess PIs’ effectiveness at 1-year follow-up. 183 SZ outpatients were recruited from FondaMental Advanced Centers of Expertise for Schizophrenia cohort. Baseline and 1-year evaluations included sociodemographic data, current treatments, illness characteristics and standardized scales for clinical severity, adherence to treatment, quality of life, a large cognitive battery, and daily functioning assessment. Only 7 (3.8%) received a PI before the evaluation, and 64 (35%) have received at least one PI during the 1-year follow-up. Having had at least one PI during the follow-up has been associated in multivariate analyses with significantly higher improvement in positive and negative symptoms (respectively p =0.031; p = 0.011), mental flexibility (TMT B, p = 0.029; C-VF, p = 0.02) and global functioning (p =0.042). CBT and SST were associated with higher cognitive improvements, while CRT was associated with clinical improvement. These results have not been demonstrated before and suggest that the effect of each PI is larger than its initial target. The present study has confirmed the PIs’ effectiveness in a large sample of community-dwelling SZ outpatients at 1 year follow-up. Efforts to improve access to PI should be reinforced in public health policies.
Databáze: OpenAIRE
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