Phlegmonous appendicitis in children is characterized by eosinophilia in white blood cell counts
| Autor: | Marc Reismann, Josephine Radtke, Karin Rothe, Maximiliane I. Minderjahn, Dag Schädlich |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Abdominal Abscess Time Factors Adolescent Inflammation Disease Risk Assessment Gastroenterology Cohort Studies Leukocyte Count 03 medical and health sciences Postoperative Complications 0302 clinical medicine Germany Internal medicine White blood cell Eosinophilia Appendectomy Humans Medicine 030212 general & internal medicine Child Retrospective Studies business.industry Complicated appendicitis Eosinophil Appendicitis medicine.disease Immunohistochemistry Treatment Outcome Basophilia medicine.anatomical_structure ROC Curve 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Female medicine.symptom business Follow-Up Studies |
| Zdroj: | World Journal of Pediatrics. 14:504-509 |
| ISSN: | 1867-0687 1708-8569 |
| Popis: | Phlegmonous and complicated appendicitis represent independent entities depending on hereditary immunological mechanisms. However, clinically there are no means to distinguish uncomplicated phlegmonous from complicated appendicitis. The ability to distinguish these two forms of appendicitis is relevant as current attempts are to treat both forms of the disease differently. The aim of the present study was to investigate differences in white blood cell counts (WBCs) in these conditions to identify areas of interest for future molecular studies. White blood cell counts of patients aged between 7 and 14 years who underwent appendectomy from January 2008 to June 2016 were investigated with special reference to particular cellular subpopulations. A total of 647 children were included in the study. Within distinct inflammatory patterns, significant eosinophilia and basophilia were found in phlegmonous inflammation compared with complicated inflammation (0.11 ± 0.19 × 109/L vs. 0.046 ± 0.104 × 109/L, P |
| Databáze: | OpenAIRE |
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