Supplementary Figures 1-2 from NT113, a Pan-ERBB Inhibitor with High Brain Penetrance, Inhibits the Growth of Glioblastoma Xenografts with EGFR Amplification
| Autor: | C. David James, Theodore Nicolaides, Nicholas Butowski, Jann N. Sarkaria, Francis J. Giles, Andrew P. Mazar, Alexander H. Stegh, Shi-Yuan Cheng, Jeffrey J. Raizer, Andrew T. Parsa, Dennis Brown, Wang Shen, Tsun-Wen Yao, Tomoko Ozawa, Yasuyuki Yoshida |
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| Rok vydání: | 2023 |
| Popis: | Supplementary Figure 1: NT113 Chemical Structure; Supplementary Figure 2: A) Relative expression of endogenous wild-type EGFR in parental U87 cells (U87p) vs. U87 cells transduced with EGFRvIII retrovirus (U87vIII). B) Relative expression of EGFRwt, EGFRvIII, ERBB2 and ERBB4 in subcutaneous tumors of GBM12, GBM39, and GBM6. |
| Databáze: | OpenAIRE |
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