Efficacy and Safety of PAIR for Cystic Echinococcosis: Experience on a Large Series of Patients from Bulgaria
| Autor: | N. Grigorov, Enrico Brunetti, Rumiana G. Mitova, Jordan Genov, Francesca Tamarozzi, Branimir Golemanov, Dimitar Vuchev |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Punctures Suction World health Young Adult Echinococcosis Virology parasitic diseases medicine Humans Bulgaria Aged Ultrasonography Anthelmintics Saline Solution Hypertonic Ethanol business.industry Cystic echinococcosis Anaphylactic reaction Large series Articles Middle Aged medicine.disease Surgery Infectious Diseases Female Parasitology business |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 84:48-51 |
| ISSN: | 1476-1645 0002-9637 |
| Popis: | We report our experience with puncture, aspiration, injection, and reaspiration (PAIR) for the treatment of cystic echinococcosis in Bulgaria. PAIR was performed in 230 patients with 348 echinococcal cysts. At 12-month fol- low-up, 77.6% of the cysts, all cystic echinococcosis (CE) 1 and CE3a cysts according to the World Health Organization Informal Working Group classification, showed various degrees of obliteration. In 11.5% of cysts, all of which were > 10 cm-type CE1, a significant amount of fluid persisted, and they were punctured again. Of those, 16 (4.6%) contained protoscolices and were treated by a second PAIR. The remaining 24 (6.9%) cysts were treated by simple aspiration or drainage. No significant reduction in size and no changes in the structure were observed in 10.9% of cysts, all of which were classified as CE2 or CE3b. Complications developed in 25.2% of patients, including severe anaphylactic reaction in two (0.9%) patients. Our experience confirms that PAIR is a successful first-choice treatment when a stage-specific approach is taken. |
| Databáze: | OpenAIRE |
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