Vaginal microbiota differences associated with pelvic organ prolapse risk during late gestation in commercial sows†
| Autor: | Lucas R. Koester, Aileen F. Keating, Jason W. Ross, Stephan Schmitz-Esser, Amanda Chipman, Jamie M Studer, Zoe E Kiefer, Christine Mainquist-Whigham |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
genetic structures
Late gestation Swine media_common.quotation_subject animal diseases Sus scrofa Physiology Gestational Age Biology reproduction pig sow Pregnancy Animals media_common vaginal microbiota Swine Diseases Pelvic organ Microbiota Cell Biology General Medicine AcademicSubjects/SCI01070 pelvic organ prolapse Reproductive Medicine Community composition Vaginal swabs Vagina 16s rrna gene sequencing Gestation AcademicSubjects/MED00773 Female Reproduction Research Article |
| Zdroj: | Biology of Reproduction |
| ISSN: | 1529-7268 0006-3363 |
| Popis: | During the last decade, sow mortality due to pelvic organ prolapse (POP) has increased. To better understand the biology associated with POP, sows were phenotypically assessed and assigned a perineal score (PS) based on presumed POP risk and categorized as PS1 (low), PS2 (moderate), or PS3 (high). The study objective was to identify changes in sow vaginal microbiota that may be associated with POP. The hypothesis is that vaginal microbiota differs between sows with variable risk for POP, and changes in microbiota during late gestation exist between sows with differing risk. Of the 2864 sows scored during gestation week 15, 1.0, 2.7, and 23.4% of PS1, PS2, and PS3 sows, respectively, subsequently experienced POP. Vaginal swabs subjected to 16S rRNA gene sequencing revealed differences in community composition (Bray–Curtis; P |
| Databáze: | OpenAIRE |
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