The role of 'dormant' mechanisms in regulation of K/Na balance in the rat cardiac muscle cell during hypoxia
| Autor: | Pogorelov Ag, DV Goldstein, Dubrovkin Mi, Khrenova Ev, Pogorelova Vn, Demin Ip |
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| Přispěvatelé: | University of Groningen |
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
MYOCARDIAL-ISCHEMIA
Physiology PH Potassium Sodium INHIBITION chemistry.chemical_element NA+ Biochemistry CHANNEL RABBIT medicine INJURY Myocyte Ecology Evolution Behavior and Systematics Ion transporter Cardiac muscle cell Chemistry K+ ACCUMULATION Cardiac muscle Hypoxia (medical) medicine.anatomical_structure TISSUE EXTRACELLULAR-SPACE Biophysics medicine.symptom Perfusion |
| Zdroj: | Journal of evolutionary biochemistry and physiology, 40(4), 443-449 |
| ISSN: | 0022-0930 |
| Popis: | Using the electron probe microanalysis, potassium and sodium concentrations were measured in Wistar rat cardiac muscle cells. Hypoxic conditions were modeled according to the protocol of global ischemia in the absence of perfusion or via anoxic perfusion without glucose. It was shown that depending on the scheme of realization of hypoxia the change with time of the intracellular potassium and sodium balance had different character. Based on the obtained data, the sequence of activation of the hypoxia-specific mechanisms of ion transport on the cardiomyocyte membrane is considered. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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