Airborne Transmission of Highly Pathogenic Influenza Virus during Processing of Infected Poultry

Autor: Kateri Bertran, Terrence M. Tumpey, Charles L. Balzli, David E. Swayne, Yong-Kuk Kwon, Andrew Clark
Rok vydání: 2017
Předmět:
0301 basic medicine
Microbiology (medical)
animal structures
Epidemiology
Influenza A Virus H5N1 Subtype
aerosol
Highly pathogenic
animal diseases
viruses
030106 microbiology
Air microbiology
Air Microbiology
lcsh:Medicine
Biology
medicine.disease_cause
Airborne transmission
Virus
lcsh:Infectious and parasitic diseases
03 medical and health sciences
medicine
Animals
lcsh:RC109-216
airborne transmission
Animal Husbandry
Poultry Diseases
Inhalation Exposure
Influenza A Virus
H5N1 Subtype
Research
poultry
lcsh:R
Ferrets
virus diseases
Airborne Transmission of Highly Pathogenic Influenza Virus during Processing of Infected Poultry
Virology
Influenza A virus subtype H5N1
030104 developmental biology
Infectious Diseases
Ducks
Influenza in Birds
Air space
droplet
H5N1 highly pathogenic avian influenza
Chickens
Zdroj: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 23, Iss 11, Pp 1806-1814 (2017)
ISSN: 1080-6059
Popis: Exposure to infected poultry is a suspected cause of avian influenza (H5N1) virus infections in humans. We detected infectious droplets and aerosols during laboratory-simulated processing of asymptomatic chickens infected with human- (clades 1 and 2.2.1) and avian- (clades 1.1, 2.2, and 2.1) origin H5N1 viruses. We detected fewer airborne infectious particles in simulated processing of infected ducks. Influenza virus–naive chickens and ferrets exposed to the air space in which virus-infected chickens were processed became infected and died, suggesting that the slaughter of infected chickens is an efficient source of airborne virus that can infect birds and mammals. We did not detect consistent infections in ducks and ferrets exposed to the air space in which virus-infected ducks were processed. Our results support the hypothesis that airborne transmission of HPAI viruses can occur among poultry and from poultry to humans during home or live-poultry market slaughter of infected poultry.
Databáze: OpenAIRE
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