A Chemically Well-Defined, Self-Assembling 3D Substrate for Long-Term Culture of Human Pluripotent Stem Cells

Autor:	Yun S. Chan, Bobby Cheng Peow Tan, Huck H. Ng, Andrew C.A. Wan, Yihua Loo, Iwona Szczerbinska, Charlotte A. E. Hauser
Rok vydání:	2019
Předmět:	Biomaterials Cell expansion Chemistry Biochemistry (medical) Self assembling Biomedical Engineering Biophysics General Chemistry Substrate (printing) Induced pluripotent stem cell
Zdroj:	ACS Applied Bio Materials. 2:1406-1412
ISSN:	2576-6422
DOI:	10.1021/acsabm.8b00686
Popis:	Clinical applications of human pluripotent stem cells (PSCs) are limited by the lack of chemically well-defined scaffolds for cell expansion, differentiation, and implantation. In this study, we systematically screened various self-assembling hexapeptides to identify the best matrix for long-term 3D PSC culture. Lysine-containing Ac-ILVAGK-NH
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba43e25262dce1c1a71d87fee9f084e https://doi.org/10.1021/acsabm.8b00686 Zobrazit plný text záznamu