Autor: |
Lara M, Gross, Harold S, Nelson, Aastha, Khatiwada, Flavia C L, Hoyte |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Allergy and Asthma Proceedings. 43:543-545 |
ISSN: |
1088-5412 |
DOI: |
10.2500/aap.2022.43.220067 |
Popis: |
Background: Curcumin has been shown to decrease allergic symptoms and biomarkers in some animal and human studies. Objective: Our study aimed to determine if curcumin affects immediate skin-prick testing. Methods: We enrolled 34 participants sensitized to select antigens. The participants were randomized to treatment with curcumin or placebo in a double-blind fashion. The participants underwent titrated skin-prick testing before and after 1 week of treatment, and the pre- and posttreatment skin test wheals and flares were compared. Results: Curcumin did not have a statistically significant effect on immediate skin-prick test wheal or flare size. Conclusion: Although curcumin may attenuate allergic symptoms and biomarkers, it does not have a significant effect on immediate skin-prick test results and does not need to be discontinued before testing. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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