Plasma NO-binding activity in patients with hematological malignancies: Suppressive effect of glucocorticoids
| Autor: | M. A. Romanova, I. Shestakova, R. G. Stibel, V. I. Petukhov, Andrejs P. Skesters, Ilona Domracheva, I. Ya Kanepe, I. Ya. Kalvinsh |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Adolescent Chemistry General Medicine Plasma protein binding Middle Aged Pharmacology Nitric Oxide Stress resistance General Biochemistry Genetics and Molecular Biology Hematologic Neoplasms medicine Humans Female In patient NO binding No production Glucocorticoids Glucocorticoid Aged Protein Binding medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 142:614-617 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Plasma NO-binding activity was studied in patients with various forms of hematological malignancies. The method used in the study quantitatively evaluated the plasma capacity to bind NO, which reflects the intensity of NO production and the degree of patient's stress resistance. Plasma NO-binding activity significantly decreases in patients with hematological malignancies. Glucocorticoid treatment promotes the decrease in plasma NO-binding activity, which was dose-dependent. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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