Ultrasound fibrin clot destruction in vitro in the presence of fibrinolytic agent
Autor: | Anatoly I. Kulak, A.G Mrochek, O.A Lukyanchenko, I.E. Adzerikho, V.V Dmitriev |
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Rok vydání: | 2001 |
Předmět: |
Light transmission
Pathology medicine.medical_specialty Acoustics and Ultrasonics biology Chemistry business.industry Streptokinase Organic Chemistry Ultrasound In vitro Fibrin Inorganic Chemistry medicine biology.protein Chemical Engineering (miscellaneous) Environmental Chemistry Radiology Nuclear Medicine and imaging business Fibrinolytic agent circulatory and respiratory physiology Biomedical engineering medicine.drug |
Zdroj: | Ultrasonics sonochemistry. 8(3) |
ISSN: | 1350-4177 |
Popis: | Ultrasound fibrin clot destruction was investigated in vitro using electron microscopy and by monitoring the changes in the light transmission of clot debris suspension. It has been established that in the course of a combined action of ultrasound and fibrinolytic agent at high ultrasound intensities and short sonification periods, fibrin clot is disrupted mainly due to sonomechanical treatment, while fermentative lysis takes place in parallel and at a significantly lower rate. However, the streptokinase action prevails after ultrasound switching off and results in the prevention of clot debris conglomeration. |
Databáze: | OpenAIRE |
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