Real-time monitoring of fenitrothion in water samples using a silicon nanophotonic biosensor

Autor: Heriberto J Díaz-Luisravelo, M-Carmen Estévez, Patricia Ramirez-Priego, Juan J. Manclús, Angel Montoya, Laura M. Lechuga
Přispěvatelé: Generalitat de Catalunya, Agencia Estatal de Investigación (España)
Rok vydání: 2021
Předmět:
Silicon
Nanophotonics
Silicon photonics
chemistry.chemical_element
Biosensing Techniques
02 engineering and technology
01 natural sciences
Biochemistry
Analytical Chemistry
Fenitrothion
TECNOLOGIA ELECTRONICA
chemistry.chemical_compound
Tap water
Organophosphate
Limit of Detection
Humans
Environmental Chemistry
03.- Garantizar una vida saludable y promover el bienestar para todos y todas en todas las edades
Spectroscopy
Immunoassay
Detection limit
Chromatography
06.- Garantizar la disponibilidad y la gestión sostenible del agua y el saneamiento para todos
010401 analytical chemistry
Environmental monitoring
021001 nanoscience & nanotechnology
0104 chemical sciences
Highly sensitive
Pesticide
07.- Asegurar el acceso a energías asequibles
fiables
sostenibles y modernas para todos
chemistry
Optical sensor
Water quality
Label-free
0210 nano-technology
Biosensor
Zdroj: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
Digital.CSIC. Repositorio Institucional del CSIC
Popis: [EN] Due to the large quantities of pesticides extensively used and their impact on the environment and human health, a prompt and reliable sensing technique could constitute an excellent tool for in-situ monitoring. With this aim, we have applied a highly sensitive photonic biosensor based on a bimodal waveguide interferometer (BiMW) for the rapid, label-free, and speci¿c quanti¿cation of fenitrothion (FN) directly in tap water samples. After an optimization protocol, the biosensor achieved a limit of detection (LOD) of 0.29 ng mL¿¿1 (1.05 nM) and a half-maximal inhibitory concentration (IC50)of 1.71 ng mL¿¿1 (6.09 nM) using a competitive immunoassay and employing diluted tap water. Moreover, the biosensor was successfully employed to determine FN concentration in blind tap water samples obtaining excellent recovery percentages with a time-to-result of only 20 min without any sample pre-treatment. The features of the biosensor suggest its potential application for real time, fast and sensitive screening of FN in water samples as an analytical tool for the monitoring of the water quality.
This work received financial support from DIONISOS Project (Retos Colaboracion RTC-2017-6222-5). The ICN2 is funded by the CERCA programme/Generalitat de Catalunya. The ICN2 is supported by the Severo Ochoa Centres of Excellence programme, funded by the Spanish Research Agency (AEI, grant no. SEV-2017-0706)
Databáze: OpenAIRE
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