Trends in high intensity statin use among secondary prevention patients 76 years and older
| Autor: | Michele Wood, Kari L. Olson, Anne M. Denham, Sheila L. Stadler, Roseanne Hornak, Leslie K. Ruppe, Thomas Delate |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Comparative Effectiveness Research
medicine.medical_specialty Prescription Drugs Statin Health Services for the Aged mesh:Health Services for the Aged medicine.drug_class Comparative effectiveness research lcsh:RS1-441 Pharmaceutical Science Coronary Artery Disease Pharmacy mesh:Aged mesh:Coronary Artery Disease 030226 pharmacology & pharmacy lcsh:Pharmacy and materia medica Coronary artery disease 03 medical and health sciences 0302 clinical medicine mesh:Comparative Effectiveness Research Integrated mesh:Integrated Internal medicine Delivery of Health Care Integrated Medicine mesh:Retrospective Studies Aged Retrospective Studies Original Research Secondary prevention business.industry mesh:Delivery of Health Care High intensity lcsh:RM1-950 Gold standard Retrospective cohort study Statin treatment medicine.disease Drug Utilization United States lcsh:Therapeutics. Pharmacology mesh:Hydroxymethylglutaryl-CoA Reductase Inhibitors Hydroxymethylglutaryl-CoA Reductase Inhibitors mesh:United States business Delivery of Health Care mesh:Prescription Drugs mesh:Drug Utilization |
| Zdroj: | Pharmacy Practice Pharmacy Practice (Granada), Volume: 17, Issue: 2, Article number: 1402, Published: 18 NOV 2019 Pharmacy Practice, Vol 17, Iss 2, p 1402 (2019) Pharmacy Practice (Granada) v.17 n.2 2019 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname |
| ISSN: | 1886-3655 1885-642X |
| DOI: | 10.18549/pharmpract.2019.2.1402 |
| Popis: | Background: High intensity statin therapy (HIST) is the gold standard therapy for decreasing the risk of recurrent atherosclerotic cardiovascular disease (ASCVD); however, little is known about the use of HIST in older adults with ASCVD. Objectives: The aim of this cross-sequential study was to determine trends in statin intensity in older adults over a 10-year timeframe. Methods: The study was conducted in an integrated healthcare delivery system. Patients were 76 years or older with validated coronary ASCVD. Data were collected from administrative databases. Statin intensity level was assessed in eligible patients on January 1st and July 1st from January 1, 2007 to December 31, 2016. Results: Overall, a total of 5,453 patients were included with 2,119 (38.9%) and 3,334 (61.1%) categorized as HIST and Non-HIST, respectively. Included patients had a mean age of 79.8 years and were primarily male and white and had a cardiac intervention. The rate of HIST use increased from 14.5% to 41.3% over the study period (p |
| Databáze: | OpenAIRE |
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