Severe Hypercalcemia as an Initial Presenting Manifestation of Hepatocellular Carcinoma
| Autor: | Sunitha Mannam, Samia R Henien, John George, Michel W. Ghobrial |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Pathology Constipation Carcinoma Hepatocellular Bone disease Peptide Hormones Gastroenterology Internal medicine Carcinoma medicine Humans lcsh:RC799-869 Hepatic encephalopathy Aged Parathyroid hormone-related protein business.industry Liver Neoplasms Parathyroid Hormone-Related Protein General Medicine medicine.disease Parathyroid Hormone Hepatocellular carcinoma Hypercalcemia Calcium Female lcsh:Diseases of the digestive system. Gastroenterology medicine.symptom business Polydipsia Primary hyperparathyroidism |
| Zdroj: | Canadian Journal of Gastroenterology, Vol 16, Iss 9, Pp 607-609 (2002) |
| ISSN: | 0835-7900 |
| Popis: | An 80-year-old white woman who presented with fatigue, weakness, weight loss, constipation and polydipsia is reported. The patient was given a diagnosis of severe hypercalcemia and was subsequently found to have clinical, roentgenographic and pathological evidence of hepatocellular carcinoma. Further studies revealed a low parathyroid hormone level, excluding the possibility of primary hyperparathyroidism, and a negative bone survey, precluding metastatic bone disease. The patient’s hypercalcemia was believed to emanate from the humoral secretion of a parathyroid hormone-related peptide, which was found to be elevated, and was abated with conservative management while her cancer was being treated with chemotherapy. The details of this rarely documented presentation, which can easily be mistaken for hepatic encephalopathy, are provided. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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