Molecular epidemiology of dengue-1 and dengue-4 viruses
| Autor: | Vincent Deubel, M. Laille, Olivier Cassar, Marie Thérèse Drouet, María G. Guzmán, Eliane Chungue, Léon Rosen |
|---|---|
| Přispěvatelé: | Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD), Institut Pasteur [Paris], Pedro Kouri Institute of Tropical Medicine, Institut Pasteur de Nouvelle-Calédonie, Réseau International des Instituts Pasteur (RIIP), Institut Pasteur [Paris] (IP) |
| Rok vydání: | 1995 |
| Předmět: |
[SDV]Life Sciences [q-bio]
viruses Molecular Sequence Data 030231 tropical medicine MESH: Dengue MESH: Base Sequence Biology MESH: Dengue Virus digestive system complex mixtures Dengue fever Dengue Evolution Molecular 03 medical and health sciences fluids and secretions 0302 clinical medicine Viral Envelope Proteins Virology Genotype Genetic variation medicine Animals Humans MESH: Animals Nucleotide Serotyping Gene MESH: Evolution Molecular 030304 developmental biology Genetics chemistry.chemical_classification 0303 health sciences MESH: Humans MESH: Molecular Sequence Data Base Sequence Molecular epidemiology Strain (biology) Nucleic acid sequence MESH: Serotyping Dengue Virus medicine.disease digestive system diseases chemistry MESH: Viral Envelope Proteins |
| Zdroj: | Journal of General Virology Journal of General Virology, Microbiology Society, 1995, 76 (7), pp.1877-1884. ⟨10.1099/0022-1317-76-7-1877⟩ Journal of General Virology, 1995, 76 (7), pp.1877-1884. ⟨10.1099/0022-1317-76-7-1877⟩ |
| ISSN: | 1465-2099 0022-1317 |
| Popis: | Erratum in J Gen Virol 1996 Mar;77(Pt 3):565-6; International audience; Genetic variation between geographically and temporally distinct isolates of dengue-1 (DEN-1) and dengue-4 (DEN-4) viruses was investigated. The nucleotide sequences of a fragment of the envelope protein gene encoding amino acids 28 to 87 of 35 DEN-1 isolates and 28 DEN-4 isolates were determined. Maximum nucleotide sequence variation was 6.9% and 4.9% for DEN-1 and DEN-4 viruses, respectively. Taking a divergence of 6% between the nucleotide sequences as the cut-off value, three genotype groups were defined for DEN-1 viruses, whereas only one was observed for DEN-4 viruses. Molecular analysis of isolates from the South Pacific permits the classification of the recent strains of DEN-1 (1988-1989 epidemics) into a genotype distinct from the genotype which comprises earlier strains. This observation suggests that the recent epidemics were due to the introduction of a new genotype rather than to the re-emergence of the earlier strain. |
| Databáze: | OpenAIRE |
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