Placental Villi-Decidua Interactions in Normal and Hypertensive Pregnancies: A Morphological Quantitative Study
| Autor: | Elena Toschi, Pugnaloni A, C. Castaldini, G. Biagini, Carlo Romanini, Cester N, V. Carboni, Laura Mazzanti |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
medicine.medical_specialty
Stromal cell Pregnancy Complications Cardiovascular Uterus Embryonic Development Biology Pregnancy Internal medicine Placenta Decidua medicine Humans Decidual cells reproductive and urinary physiology Obstetrics and Gynecology Immunohistochemistry medicine.anatomical_structure Endocrinology Reproductive Medicine In utero Hypertension embryonic structures Microscopy Electron Scanning Gestation Chorionic villi Female Chorionic Villi |
| Zdroj: | Gynecologic and Obstetric Investigation. 34:15-19 |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000292717 |
| Popis: | The decidual response to the implantation of the embryo is characterized by physical modifications to the uterine wall, with proliferation of the stromal cells which later change into decidual cells. We performed associated morphological and morphometrical studies to assess how the placental villi and decidua intersect, both in normal terminal pregnancy and in hypertensive patients in whom microenvironmental modifications induced by hypertension may cause significant alterations in mother-fetus relationships. In placentas of hypertensive women our morphometric analyses showed a higher number of chorionic villi-decidua interactions (p less than 0.05) with a more clumped distribution (p less than 0.05) and a smaller surface area of single interaction (p less than 0.001), in association with a higher number (p less than 0.005), and greater areas (p less than 0.01) of decidual cells. These data demonstrate how the placenta can enhance mother-fetus contacts impaired as the result of a hypertensive condition. |
| Databáze: | OpenAIRE |
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