Phosphate and Calcium Control in Short Frequent Hemodialysis with the NxStage System One Cycler: Mass Balance Studies and Comparison with Standard Thrice-Weekly Bicarbonate Dialysis
| Autor: | C. Brunati, Francesca Gervasi, Maria Luisa Querques, Costanza Casati, Alberto Montoli, Giacomo Colussi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_treatment 030232 urology & nephrology chemistry.chemical_element 030204 cardiovascular system & hematology Calcium Phosphates 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Animal science Renal Dialysis Medicine Humans Frequent hemodialysis Dialysis Total plasma business.industry Home hemodialysis Hematology General Medicine Middle Aged Bicarbonate dialysis Phosphate Bicarbonates chemistry Nephrology Female Ca increase business |
| Zdroj: | Blood purification. 45(4) |
| ISSN: | 1421-9735 |
| Popis: | Background: Short frequent dialysis with NxStage System One cycler (NSO) has become increasingly popular as home hemodialysis prescription. Short dialysis sessions with NSO might not allow adequate phosphate (P) removal. Methods: Single-session and weekly balances of P and calcium (Ca) were compared in 14 patients treated with NSO (6 sessions/week) and in 14 patients on standard bicarbonate dialysis (BHD). Results: NSO and BHD showed similar plasma P fall, with end-dialysis plasma P slightly lower in BHD (2.2 ± 0.5 vs. 2.7 ± 0.8 mg/dL, p < 0.02). Single-session P removal was lower in NSO, but weekly removal was higher (3,488 ± 1,181 mg vs. 2,634 ± 878, p < 0.003). Plasma Ca increase was lower in NSO, with similar PTH fall. Ca balance varied according to start plasma Ca, dialysate to blood Ca gradient and net ultrafiltration. Conclusions: short, frequent home hemodialysis with NSO, on a 6/week-based prescription, allows higher weekly P removal than BHD. With the dialysate Ca concentration in use (6 mg/dL), total plasma Ca and iCa concentration increase is lower in NSO. |
| Databáze: | OpenAIRE |
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