Psychosocial status predicts mortality in patients with life-threatening ventricular arrhythmias
| Autor: | Sandeep Joshi, MaryAnn McBurnie, Alfred P. Hallstrom, Jonathan S. Steinberg, Eleanor Schron, Judy Powell |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Defibrillation medicine.medical_treatment Ventricular tachycardia Quality of life Predictive Value of Tests Risk Factors Physiology (medical) Internal medicine medicine Humans Prospective Studies Aged Proportional Hazards Models Ejection fraction Chi-Square Distribution Proportional hazards model business.industry Middle Aged medicine.disease Prognosis Checklist Defibrillators Implantable Heart Arrest Heart failure Cardiology Quality of Life Tachycardia Ventricular Female Cardiology and Cardiovascular Medicine business Psychosocial |
| Zdroj: | Heart rhythm. 5(3) |
| ISSN: | 1547-5271 |
| Popis: | Background Quality-of-life (QoL) instruments evaluate various aspects of physical, mental, and emotional health, but how these psychosocial characteristics impact long-term outcome after cardiac arrest and ventricular tachycardia (VT) is unknown. Objective The purpose of this study was to evaluate the relationship of baseline QoL scores with long-term survival of patients enrolled in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. Methods Formal QoL measures included SF-36 mental and physical components, Patient Concerns Checklist, and Ferrans and Powers Quality-of-Life Index–Cardiac Version. Multivariate Cox regression was used to assess the association of survival and these measures, adjusting for index arrhythmia type, gender, race, age, ejection fraction, history of congestive heart failure, antiarrhythmic therapy, and beta-blocker use. Results During mean follow-up of 546 ± 356 days, 129 deaths occurred among 740 patients. Higher baseline SF-36 physical summary scores ( P P = .015), and lower baseline Patient Concerns Checklist summary scores ( P = .047) were associated with longer survival, even after adjustment for clinical variables. When QoL measures were examined simultaneously, only the SF-36 physical summary score remained significant ( P = .002). Conclusion During recovery after sustained VT or cardiac arrest, formal baseline QoL assessment provides important prognostic information independent of traditional clinical data. |
| Databáze: | OpenAIRE |
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