Recovery of the failing heart: emerging approaches and mechanisms in excitation-contraction coupling

Autor: Michael Ibrahim, Anas Nader, Joy C. E. Edlin, Cesare M. Terracciano
Rok vydání: 2014
Předmět:
Zdroj: F1000Prime Reports
ISSN: 2051-7599
DOI: 10.12703/p6-27
Popis: Heart failure (HF) is a growing cause of morbidity and mortality globally. All clinical therapies that reduce mortality have been shown to induce reverse remodeling. In this article, we discuss a conceptual approach to the evolving treatment of HF using emerging treatment modalities for the drug-refractory patient. This approach is based on the combinatorial, integrated application of therapies shown to influence reverse remodeling in the laboratory.
Databáze: OpenAIRE