Recovery of the failing heart: emerging approaches and mechanisms in excitation-contraction coupling
Autor: | Michael Ibrahim, Anas Nader, Joy C. E. Edlin, Cesare M. Terracciano |
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Rok vydání: | 2014 |
Předmět: | |
Zdroj: | F1000Prime Reports |
ISSN: | 2051-7599 |
DOI: | 10.12703/p6-27 |
Popis: | Heart failure (HF) is a growing cause of morbidity and mortality globally. All clinical therapies that reduce mortality have been shown to induce reverse remodeling. In this article, we discuss a conceptual approach to the evolving treatment of HF using emerging treatment modalities for the drug-refractory patient. This approach is based on the combinatorial, integrated application of therapies shown to influence reverse remodeling in the laboratory. |
Databáze: | OpenAIRE |
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