Dresden PTSD treatment study: randomized controlled trial of motor vehicle accident survivors
| Autor: | Anke Karl, Andreas Maercker, Sirko Rabe, Hans Menning, T Zöllner |
|---|---|
| Přispěvatelé: | University of Zurich, Maercker, Andreas |
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty lcsh:RC435-571 medicine.medical_treatment Poison control law.invention Stress Disorders Post-Traumatic 2738 Psychiatry and Mental Health Randomized controlled trial law Germany lcsh:Psychiatry medicine Humans Survivors Depression (differential diagnoses) Language Cognitive Behavioral Therapy 10093 Institute of Psychology Posttraumatic growth Accidents Traffic Cognition medicine.disease Cognitive behavioral therapy Psychiatry and Mental health Treatment Outcome Chronic Disease Cognitive therapy Physical therapy Major depressive disorder Female 150 Psychology Psychology Research Article Clinical psychology |
| Zdroj: | BMC Psychiatry, Vol 6, Iss 1, p 29 (2006) BMC Psychiatry |
| ISSN: | 1471-244X |
| Popis: | Background We translated, modified, and extended a cognitive behavioral treatment (CBT) protocol by Blanchard and Hickling (2003) for the purpose of treating survivors of MVA with full or subsyndromal posttraumatic stress disorder (PTSD) whose native language is German. The treatment manual included some additional elements, e. g. cognitive procedures, imaginal reliving, and facilitating of posttraumatic growth. The current study was conducted in order to test the efficacy of the modified manual by administering randomized controlled trial in which a CBT was compared to a wait-list control condition. Methods Forty-two motor vehicle accident survivors with chronic or severe subsyndromal posttraumatic stress disorder (PTSD) completed the treatment trial with two or three detailed assessments (pre, post, and 3-month follow-up). Results CAPS-scores showed significantly greater improvement in the CBT condition as compared to the wait list condition (group × time interaction effect size d = 1.61). Intent-to-treat analysis supported the outcome (d = 1.34). Categorical diagnostic data indicated clinical recovery of 67% (post-treatment) and 76% (3 months FU) in the treatment group. Additionally, patients of the CBT condition showed significantly greater reductions in co-morbid major depression than the control condition. At follow-up the improvements were stable in the active treatment condition. Conclusion The degree of improvement in our treatment group was comparable to that in previously reported treatment trials of PTSD with cognitive behavioral therapy. Trial registration ISRCTN66456536 |
| Databáze: | OpenAIRE |
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