| Autor: |
R.N. Duvall, Gerald Gold, Blaze T. Palermo, Richard L. Hurtle |
| Rok vydání: |
1973 |
| Předmět: |
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| Zdroj: |
Journal of Pharmaceutical Sciences. 62:1530-1533 |
| ISSN: |
0022-3549 |
| DOI: |
10.1002/jps.2600620934 |
| Popis: |
Instrumentation for evaluating the dustiness of tableting materials is reported. The sample is dropped into a dust chamber where a controlled flow of air carries the resulting dust particles through a beam of light. The scattered light is received by a photo-detcctor which converts light pulses into electrical pulses. The instrumentation was precalibrated in particle-size ranges of 0.5-10, 11–50, and > 50 μ, and the number of particles in each size range is displayed on a digital counter. The particle size refers to the equivalent diameter of the dust particle that generates the same electrical response in the photodetector as the reference particle used to calibrate the instrumentation. Eleven commonly used tableting aids were classified into three categories based on their relative dustiness. Data obtained with the dust counter were shown to correlate with the dustiness resulting from the bulk handling of larger quantities of materials. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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