A comparative study of the prevalence of the metabolic syndrome and its components in type 2 diabetic patients in two Caribbean islands using the new International Diabetes Federation definition
| Autor: | Henrike Sell, F Okali, B Raja, S. Hussaini, V Wheeler, Chidum E. Ezenwaka, D Seales, E Nwagbara, Jürgen Eckel, H. Avci |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Waist Physiology Blood Pressure Type 2 diabetes Insulin resistance Age Distribution Risk Factors Physiology (medical) Internal medicine Diabetes mellitus medicine Prevalence Humans Obesity Life Style Demography Glycated Hemoglobin Metabolic Syndrome Sex Characteristics Adiponectin Geography business.industry International Agencies General Medicine Middle Aged medicine.disease Lipid Metabolism Endocrinology Trinidad and Tobago Diabetes Mellitus Type 2 Female Metabolic syndrome business Body mass index |
| Zdroj: | Archives of physiology and biochemistry. 113(4-5) |
| ISSN: | 1381-3455 |
| Popis: | Tobago and Trinidad are two Caribbean islands with distinct genetic background and lifestyles; while Tobago is serene and a tourist centre, Trinidad is characterized by a hustling and bustling lifestyle. The study was aimed at determining and comparing the prevalence of the metabolic syndrome (MetS) and its critical components in type 2 diabetic patients using the new International Diabetes Federation (IDF) definition.Four hundred and thirteen (166 Tobago, 247 Trinidad) type 2 diabetic patients visiting 10 lifestyle disease clinics were studied. Blood pressure, anthropometric parameters (height, weight, body mass index and waist circumference) and overnight fasting blood samples were taken. Plasma glucose and serum triglycerides, total cholesterol, LDL- and HDL-cholesterol, insulin, and adiponectin were determined. Insulin resistance (IR) was determined using the HOMA method.The patients in Tobago were significantly older than patients in Trinidad (p0.001) but the duration of diabetes (9.4 +/- 0.5 vs. 11.1 +/- 0.7 yr), medications, generalized (31.7 vs. 38.8%) and central (78.5 vs. 83.7%) obesity were similar (p0.05). In comparison with patients in Tobago, diabetic patients in Trinidad, irrespective of gender, had significantly higher prevalence of IDF critical components such as raised BP, raised triglycerides and reduced HDL-cholesterol (all, p0.001). Thus, while more patients in Trinidad were diagnosed with MetS based on three or four components, more patients in Tobago were diagnosed based on two components (p0.001).There were high prevalence rates of the components of the MetS in both the islands of Tobago and Trinidad. Quantitatively, the aggregation of the components is higher in patients in Trinidad, which constitute greater risk for adverse cardiovascular outcome. Controlling central obesity should be the target in preventing MetS in the two islands. |
| Databáze: | OpenAIRE |
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