Incidence of gestational diabetes and birth complications in Switzerland: screening in 1042 pregnancies
Autor: | Enzo Fontana, Daniel Périard, Amged Kashef, Andrea Orecchio, Jean-Luc Magnin, Daniel Hayoz |
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Rok vydání: | 2014 |
Předmět: |
medicine.medical_specialty
endocrine system diseases Endocrinology Diabetes and Metabolism Population Prenatal diagnosis Infant Newborn Diseases Endocrinology Pregnancy Prenatal Diagnosis Diabetes mellitus medicine Humans education education.field_of_study Glucose tolerance test medicine.diagnostic_test business.industry Obstetrics Incidence Incidence (epidemiology) Infant Newborn Pregnancy Outcome nutritional and metabolic diseases Obstetrics and Gynecology Glucose Tolerance Test medicine.disease female genital diseases and pregnancy complications Obstetric Labor Complications Gestational diabetes Diabetes Gestational Feasibility Studies Population study Female business Switzerland |
Zdroj: | Gynecological Endocrinology. 30:561-564 |
ISSN: | 1473-0766 0951-3590 |
Popis: | To evaluate the incidence of gestational diabetes mellitus (GDM), gestational glucose intolerance (GGI), and birth major complications, a population of 1042 pregnant women was screened after the end of the second trimester with a two-step screening method. Patients with a positive 50-g screening test (plasma glucose ≥ 7.8 mmol/l at 1 h) underwent a 3-h standard 100-g oral glucose tolerance test. Clinical records of patients and newborns were analysed and compared to normotolerant patients group. GDM was found in 4.8% and GGI in 2.6% of all screened women of this study population. The patient group with GDM significantly differed from control, with a higher proportion of Asiatic women (32.0% versus 2.9%, p = 0.001) and high prevalence of previous GDM (26.0% versus 0.0%, p < 0.001). Major neonatal complications occurred more frequently in the dysmetabolic groups compared to normotolerant group. Macrosomia was not noted in our population. Asiatic origin and previous GDM were strongly associated with an increased incidence of GDM in multivariate analysis. This study represents the first epidemiological evaluation of GDM/GGI in Switzerland, with a two-step screening method. Incidence of GDM and GGI as well as birth complications resulted significant in our country. |
Databáze: | OpenAIRE |
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