Epithelial tumors of the lacrimal gland in the Chinese: a clinicopathologic study of 298 patients
| Autor: | Bin Li, Jian-ping Xu, Xian-li Sun, Fei Gao, Liao-qing Li, Jost B. Jonas, Jitong Shi, Jie Zeng, Yu-zhi An |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty China genetic structures Adenoma Adolescent Adenoma Pleomorphic Lacrimal gland Lacrimal gland tumor Adenocarcinoma Pleomorphic adenoma Cellular and Molecular Neuroscience Age Distribution stomatognathic system Asian People medicine Humans Sex Distribution Cystadenocarcinoma Child Aged Retrospective Studies Lacrimal Apparatus Diseases business.industry Eye Neoplasms Middle Aged medicine.disease Sensory Systems Ophthalmology medicine.anatomical_structure Orbital Neoplasms Age distribution Female business |
| Zdroj: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 248(9) |
| ISSN: | 1435-702X |
| Popis: | To examine the clinicopathologic characteristics and clinical features of epithelial tumors of lacrimal gland in China.The retrospective case series study included all 298 patients of epithelial lacrimal gland tumors which had been collected in the ophthalmic pathologic laboratory of the Tongren Hospital Beijing in the study period from 1961 to 2005.Pleomorphic adenomas were the most common tumors (n = 213 (72%)), followed by adenoid cystic carcinoma (n = 58 (20%)), pleomorphic adenocarcinoma (n = 13 (4%)), primary adenocarcinoma (n = 8 (3%)) and other tumors (n = 6 (2%)). The most frequent symptoms and clinical signs were restrictions of the lid or eye motility (121 patients; 41%), any other kind of lid involvement (71 patients; 24%), swelling (57 patients; 19%), pain (57 patients; 8%), and decrease in vision (15 patients; 5%). A restriction of the eye motility was noted for 61 patients (21%), due to an involvement of the extraocular muscles with the tumor and due to a tumor-induced displacement of the globe. Apart from the duration of symptoms, the tumor types did not vary significantly in age, gender, and laterality.Based on the archives of the Beijing Tongren ophthalmo-pathological laboratory, the most common epithelial tumors of the lacrimal gland in mainland China were pleomorphic adenomas, followed by adenoid cystic carcinoma. The spectrum and clinical signs of epithelial lacrimal gland tumors did not differ markedly between Chinese patients and Caucasian patients. |
| Databáze: | OpenAIRE |
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