Excretion of Amino Acids in Nephrosis
| Autor: | Charles D. Miller, Maxine E. Hutchin, Walton W. Shreeve, Paul D. Doolan, Harold A. Harper |
|---|---|
| Rok vydání: | 1955 |
| Předmět: |
chemistry.chemical_classification
Inulin Clearance medicine.medical_specialty Chemistry Nephrosis Biological Transport Glomerulonephritis Urine medicine.disease Antifibrinolytic Agents General Biochemistry Genetics and Molecular Biology Body Fluids Amino acid Excretion Blood Endocrinology Aminoaciduria Antifibrinolytic agent Internal medicine medicine Humans Amino Acids Nephrotic syndrome |
| Zdroj: | Experimental Biology and Medicine. 88:510-514 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-88-21635 |
| Popis: | Summary(1) By microbiological assay, concentrations of 18 amino acids have been examined in the blood and urine of patients with nephrosis and in normal individuals under various circumstances. There were observed in an adult male patient, with nephrotic syndrome associated with glomerulonephritis, large increases over the normal rates of urinary excretion of many amino acids, both essential and nonessential, but more notably of the essential. A female adult patient, with clinical findings only of nephrosis, showed considerably less deviation from normal with a trend toward increased excretion of amino acids in the fasting state. There was a general tendency to moderately low concentrations of several amino acids in the blood of both nephrotic subjects. 2) After elevation of the blood concentrations by intravenous loading of a mixture of amino acids, the percentage of filtered amino acids (determined by simultaneous measurement of inulin clearance) which were excreted generally increased in the case of no... |
| Databáze: | OpenAIRE |
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