Clinical features of patients with type 2 diabetes with and without Covid-19: A case control study (CoViDiab I)
| Autor: | Monica Rocco, Felice Eugenio Agrò, Ernesto Maddaloni, Francesco Alessandri, Raffaella Buzzetti, Lucia Coraggio, Ivano Mezzaroma, Claudio Maria Mastroianni, Paolo Pozzilli, Francesco Pugliese, Miriam Lichtner, Sara Sterpetti, Luca D'Onofrio, Carmen Mignogna, Gaetano Leto, Giuseppe Pascarella |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Type 2 diabetes Article 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Endocrinology Internal medicine Diabetes mellitus medicine Internal Medicine Humans Medical history 030212 general & internal medicine Renal Insufficiency Chronic Aged Aged 80 and over COPD business.industry SARS-CoV-2 Incidence (epidemiology) Incidence Diabetes Case-control study Odds ratio General Medicine medicine.disease covid-19 diabetes Hospitalization Diabetes Mellitus Type 2 Italy Case-Control Studies Female business Covid-19 Kidney disease |
| Zdroj: | Diabetes Research and Clinical Practice |
| ISSN: | 0168-8227 |
| DOI: | 10.1016/j.diabres.2020.108454 |
| Popis: | Aims To evaluate whether subjects with diabetes hospitalized for Coronavirus disease-19 (Covid-19) represent a subgroup of patients with high-risk clinical features compared to patients with diabetes without Covid-19. Methods In this case-control study 79 patients with type 2 diabetes out of 354 adults hospitalized for Covid-19 and 158 controls with type 2 diabetes but without Covid-19, matched for age and gender, were enrolled. Medical history and concomitant therapies were retrieved from medical charts and compared between cases and controls, controlling for confounders. Results Fully-adjusted multivariate logistic regression model showed that previous CVD history did not differ between patients with and without Covid-19 (odds ratio 1.40, 95% confidence interval [CI]: 0.59-3.32, p=0.45). A higher prevalence of chronic obstructive pulmonary disease (COPD) (OR 3.72, 95%CI: 1.42-9.72, p=0.007) and of chronic kidney disease (CKD) (OR 3.08, 95%CI: 1.18-8.06, p=0.022) and a lower prevalence of ever smokers (OR 0.30, 95%CI: 0.13-0.67, p=0.003), of users of lipid lowering agents (OR 0.26, 95%CI: 0.12-0.54, p |
| Databáze: | OpenAIRE |
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