Cytodiagnosis of Coexistence of Leukemic Infiltration and Extramedullary Hematopoiesis in a Cervical Lymph Node, in T Cell Leukemia Patient
| Autor: | Kalpana Bothale, Akanksha Bothale, Sadhana Mahore, Trupti Dongre |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pathology
medicine.medical_specialty Histology T-cell leukemia 030209 endocrinology & metabolism Case Report Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases leukemic infiltrate Medicine lcsh:QH573-671 Myelofibrosis Extramedullary hematopoiesis (EMH) Lymph node Leukemic Infiltration business.industry lcsh:Cytology leukemia medicine.disease Extramedullary hematopoiesis Leukemia medicine.anatomical_structure 030220 oncology & carcinogenesis Bone marrow business fine-needle aspiration cytology (FNAC) Chronic myelogenous leukemia |
| Zdroj: | Journal of Cytology Journal of Cytology, Vol 35, Iss 3, Pp 189-192 (2018) |
| ISSN: | 0974-5165 0970-9371 |
| Popis: | Extramedullary hematopoiesis (EMH) is a compensatory mechanism that occurs when the marrow is unable to maintain sufficient red cell mass. EMH generally occurs in the patients with deficient bone marrow hematopoiesis secondary to either peripheral red cell destruction or marrow replacement. Although EMH is known to occur in agnogenic myeloid metaplasia with myelofibrosis, chronic myelogenous leukemia, thalassemia, and infiltrative disorders, such as lymphomas, it is rare in acute leukemias. EMH is most commonly seen in the liver and spleen as a diffuse lesion. The involvement of lymph nodes in leukemia and EMH is known; however, to the best of our knowledge, the occurrence of both in the same lymph node has been reported in a single case report. Our case may be the second most rare case of coexistence of infiltration by leukemic lymphoblasts and EMH in the same lymph node detected on FNAC. EMH should be considered in the differential diagnosis of patients with bone marrow disorders and mass lesions in extramedullary sites. |
| Databáze: | OpenAIRE |
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